One of the cleverest and simplest, projects I've stumbled upon while surfing is Garfield minus Garfield.
"Who would have guessed that when you remove Garfield from the Garfield comic strips, the result is an even better comic about schizophrenia, bipolar disorder, and the empty desperation of modern life? Friends, meet Jon Arbuckle. Let’s laugh and learn with him on a journey deep into the tortured mind of an isolated young everyman as he fights a losing battle against loneliness in a quiet American suburb."
I would recommend subscribing to the blogs rss feed as you get one or two per day and they always manage to make me piss myself luaghing.